[ The information in this article is only provided for general information and it is advised you seek professional advice before starting any treatment or alternative treatment for anxiety]
Anxiety is more than just feeling stressed or worried.Anxiety is when these anxious or stressful feelings don’t go away. Anxiety is when they are ongoing and exist without any particular reason or cause. It’s a serious condition that makes it hard for a person to cope with daily life.
Do i have anxiety ?
it is best to consult a doctor to really know and get diagnosed , however here is some general information below that you can use before visiting a doctor
For 6 months or more, on more days than not, have you:
- felt very worried
- found it hard to stop worrying
- found that your anxiety made it difficult for you to do everyday activities (e.g. work, study, seeing friends and family)?
These symptoms and feeling above can indicate anxiety or even post traumatic stress disorder
CSIRO principal research scientist, Professor Michael Fenech — who leads the genome health and nutrigenomics project — first started looking at MTHFR because of the C677T’s association with increases in homocysteine, which has also been linked with an increased risk of DNA damage, cardiovascular disease and Alzheimer’s disease. Now this has turned to an advantage and cure for many.
So what is MTHFR ?
Methylenetetrahydrofolate reductase gene, is also known broadly as MTHFR.This is a chemical found in a metabolic cycle called methylation that relies heavily on B-vitamins and plays an important role in, among many other things, mood regulation.
MTHFR is an enzyme that converts the folate you eat into the active folate in the body, 5-Methyltetrahydrofolate.
Zhang et al (2013) have studied the association between several genes involved in folate metabolism and the risk of developing Neural Tube Defects, of which are the most common and severe congenital malformation worldwide.
This meta-analysis examined 85 studies focusing on MTHFR C677T, MTHFR A1298C, MTR A2756G, MTRR A66G and RFC-1 A80G and thier links with the development of Neural Tube Defects. Overall the evdience showed a strong correlation with the MTHFR C677T mutation and a potential assocation with the RFC-1 mutation and the development of Neural Tube Defects
Studies have shown homocysteine levels can predict the length someone might suffer from post-traumatic stress disorder, that B vitamins have been observed to relieve premenstrual anxiety, and that MTHFR variations are associated with major depression, bipolar disorder and schizophrenia
Anxiety sufferer- The distinction between folinic acid and the common dietary vitamin, B9 or folic acid, is an important one. Variations in the MTHFR gene mean I am unable to convert folic acid into a form my body can use — folinic acid — easily.(this is problem that many anxiety suferers have)
To bypass this problem, all some patients need is to take folinic acid (the bioavailable form of folic acid) and methylcobalamin B12
Folinic acid effects
Generic Name: Leucovorin
Other Names: Calcium Leucovorin, Citrovorum Factor
Drug type: Folinic Acid is a reduced folic acid. Folinic Acid is used in combination with other chemotherapy drugs to either enhance effectiveness, or as a “chemoprotectant.” (For more detail, see “How this drug works” section below).
Folinic acid (INN) or leucovorin / (USAN) [ Not to be confused with folic acid.] , generally administered as calcium or sodium folinate (or leucovorin calcium/sodium), is an adjuvant used in cancer chemotherapy involving the drug methotrexate. It is also used in synergistic combination with the chemotherapy agent 5-fluorouracil. It is also know as 5-formyltetrahydrofolate
Folinic acid is a vitamer for folic acid, and has the full vitamin activity of this vitamin.
Folinic acid should not be administered intrathecally. This may produce severe adverse effects or even death
The following are possible side effects of Folinic Acid:
- Allergic reaction: rash, itching, facial flushing. Rarely severe.
- Nausea and vomiting
Elisa Black’s story of lifelong struggle and new hope for the future
Note: We strongly encourage you to talk with your health care professional about your specific medical condition and treatments. The information contained in this website is meant to be helpful and educational, but is not a substitute for medical advice.
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